Pharmaceutical Intermediate CAS 97540 -22-2 Ademetionine Disulfate Tosylate

Model NO.
HRK-Ademetionine Disulfate Tosylate
Colour
White
Grade Standard
Medicine Grade
Application
API Raw Materials
Assay
99%Min, 98.0% --101.0%
Certificate
GMP ISO USP Bp
Shelf Life
2 Years Proper Storage
Standard
GMP ISO USP Bp
Storage
Cool Dry Place
Type of Product
Auxiliaries and Other Medicinal Chemicals
MW
766.78
CAS
97540-22-2
Sample
Ademetionine Disulfate Tosylate (Same) Avaliable
Active Ingredient
Ademetionine Disulfate Tosylate (Same)
Product Name
Ademetionine Disulfate Tosylate
Mf
C22h34n6o16s4
Test
HPLC
Transport Package
1kg Per Foil Bag, 10 Bags Per Carton. 25 Kg Per Dr
Specification
99% min Ademetionine Disulfate Tosylate
Trademark
Henrikang
Origin
Shaanxi China
Production Capacity
500000kg/Year
Reference Price
$ 22.50 - 45.00

Product Description

                   
Pharmaceutical Intermediate CAS 97540-22-2 Ademetionine Disulfate Tosylate Best price Pharmaceutical Intermediate CAS 97540-22-2 Ademetionine Disulfate Tosylate
Product Name Pharmaceutical Intermediate CAS 97540-22-2 Ademetionine Disulfate Tosylate
CAS 97540-22-2
Appearance White fine powder
Molecular formula C22H34N6O16S4
Molecular Weight 766.78
Assay 99%min, 98.0% --101.0%
Shelf Life 24 months when properly stored
Storage Keep in a cool, dry, dark location
 
Pharmaceutical Intermediate CAS 97540-22-2 Ademetionine Disulfate Tosylate

What is Ademetionine disulfate tosylate (SAMe) ?

S-Adenosyl-l-methionine Disulfate Tosylate (SAMe for short) is a common cosubstrate involved in methyl group transfers. 

SAM was first discovered in Italy by G. L. Cantoni in 1952, can preventing liver cancer, promoting cartilaginous tissue forming and concrescence, may help fight depression, alzheimer's disease, liver disease, and the pain of osteoarthritis, 

SAM is now universerally acknowleged as an important pharmaceuticals to treat liver diseases. Nowaday SAM is commonly used in pharmaceuticals, health care food industry both at domestic and international market. 
Function Application

Function of Ademetionine disulfate tosylate (SAMe)

1.S-Adenosyl-L-methionine is a good nutrition for the liver,can prevent alcohol, drugs and the liver-cell injury;

2.S-Adenosyl-L-methionine has remarkable preventive effects on chronic active hepatitis, and other factors
caused liver injury,heart disease, cancer and so on.


3.S-Adenosyl-L-methionine has been found to be as effective as pharmaceutical treatments for arthritis and
major depression as well.

Application of Ademetionine disulfate tosylate (SAMe)

1. S-Adenosyl methionine (SAM, SAMe, SAM-e) is a coenzyme involved in methyl group transfers. It is made
from adenosine triphosphate (ATP) and methionine by methionine adenosyltransferase (EC 2.5.1.6).
Transmethylation, transsulfuration, and aminopropylation are the metabolic pathways that use SAM. Although
these anabolic reactions occur throughout the body, most SAM is produced and consumed in the liver.

2 .The methyl group (CH3) attached to the methionine sulfur atom in SAM is chemically reactive. This allows
donation of this group to an acceptor substrate in transmethylation reactions. More than 40 metabolic reactions
involve the transfer of a methyl group from SAM to various substrates such as nucleic acids, proteins, and lipids.

3 .In bacteria, SAM is bound by the SAM riboswitch, which regulates genes involved in methionine or cysteine
biosynthesis.

4 .Another major role of SAM is in polyamine biosynthesis. Here, SAM is decarboxylated by adenosylmethionine
decarboxylase (EC 4.1.1.50) to form S-adenosyl-5'-3-methylpropylamine. This compound then donates its 
group in the biosynthesis of polyamines such as spermidine and spermine .

5 .SAM is required for cellular growth and repair. It is also involved in the biosynthesis of several hormones and
neurotransmitters that affect mood, such as dopamine and serotonin. Methyltransferases are also responsible
for the addition of methyl groups to the 2' hydroxyls of the first and second nucleotides next to the 5' cap in messenger
RNA.

6 .In the United States, SAM is sold as a nutritional supplement under the marketing name SAM-e (also spelled
SAME or SAMe). Some research has indicated that taking SAM on a regular basis help fight depression, liver
disease, and the pain of osteoarthritis. Multiple clinical trials indicate benefits for depression, some liver conditions
and osteoarthritis. All other indications are not yet proven.
 
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Pharmaceutical Intermediate CAS 97540-22-2 Ademetionine Disulfate Tosylate


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Packaging & Logistics

Package:

1kg per Foil Bag, 10 Bags per carton. 25 kg per Drum. Or Customized Package.
 

2. Shipping Advise: 

1. By Express

------Suitable for under 50kg, Fast:3-4 days. High cost; Door to door service. Easy to pick up the goods.

2. By Air 

------Suitable for more than 50 kg, Fast:4-5 days, High cost, airport to airport. professional broker needed.

3. By sea

------Suitable for more than 500kg. Slow: 15-45 days, Low cost. Port to Port, professional broker needed.



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Pharmaceutical Intermediate CAS 97540-22-2 Ademetionine Disulfate Tosylate


 

 

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